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RE: Formal Appeal — Patient: M.R. — HCPCS J0585 (onabotulinumtoxinA) — DOS: March 10, 2026
This letter formally appeals the denial dated March 15, 2026 citing failure to complete step therapy. This patient has documented failure of two preventive medications from separate drug classes at adequate dose and duration, satisfying all applicable criteria.
Per UnitedHealthcare Medical Policy Botox-D50, coverage requires failure of ≥2 preventive medications from different classes. This requirement is fully met: Topiramate 100mg/day × 12 weeks (inadequate response) and Propranolol 80mg/day × 10 weeks (intolerable bradycardia and fatigue).
Furthermore, pursuant to NJ P.L. 2018 c.100 and NJ A1255/S1794, your plan is legally required to grant a step therapy exception when the treating physician has documented completion of required therapy. A response is mandated within 24 hours under NJ statute. The PREEMPT 1 and PREEMPT 2 clinical trials establish onabotulinumtoxinA as the standard of care for chronic migraine refractory to oral preventives.
We respectfully request immediate approval and reserve the right to escalate to CMS under CMS-0057-F if not resolved within the mandated timeframe.
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